Members
Christine Kottaridi, Biologist, MSc, PhD
Aris Spathis, Biologist, PhD
Evangelia Aga, Biologist
Chara Dova, Biologist
Examinations – Techniques
- Detection and typing of 35 Human PapillomaVirus (HPV) subtypes by low density DNA microarray technique
- Detection and typing of 37 HPV subtypes by PCR and hybridization in labeled probe specific strips
- Detection and typing E6/E7 mRNA of strains HPV16, HPV18, HPV31, HPV33 and HPV45 with NASBA technique
- Detection of cells rate overexpressing E6/E7 mRNA of HPV virus by flow cytometry
- Detection and typing of 17 respiratory viruses and HHV viruses by DNA low density microarray technique
- Detection of pathogens (CMV, PCP, MTB, Chlamydia trachomatis, Legionella pneumoniae, etc.) on cytologic materialvia Real-time PCR
- Detection of mutations for genes KRAS, EGFR, BRAF with Real-time PCR technique for therapy determination in patients with colorectal cancer, non-small cell lung cancer and melanoma
- Detection of of T and B lymphocytes clonality via PCR technique
- Detection of promoter methylation for genes associated with cell cycle and DNA repair enzymes
Research Activities
- Prevalence of HPV infection and HPV types distribution in the population, cytological and histological relations
- Association of HPV infection with cell cycle parameters and epigenetic phenomena
- Phylogenetic analysis of strains HPV16, HPV18, HPV31, HPV33 and HPV45
- Analysis of molecular parameters for colon carcinomas and association with targeted chemotherapy
- Detection of the most frequent rotavirus found in gastrointestinal infections via Real-time PCR
- Epidemiology of gene alterations and relation with the success of targeted therapy
- Epidemiology of respiratory system viral infections
- Details
- Published: 12 June 2013
- Last Updated: 09 February 2014